In vitro expressed dystrophin fragments do not associate with each other

In vitro expressed dystrophin fragments do not associate with each other.

Dystrophin, a component of the muscle membrane cytoskeleton, is the protein altered in Duchenne Muscular Dystrophy (DMD) and Becker Muscular Dystrophy (BMD). Dystrophin shares significant homology with other cytoskeletal proteins, such as alpha-actinin and spectrin. On the basis of its sequence similarity with alpha-actinin and spectrin, dystrophin has been proposed to function as dimer. Howeve...

Subclinical psychosis and depression: Co-occurring phenomena that do not predict each other over time

BACKGROUND The path from subclinical psychotic experiences to clinical disorder is thought to be mediated by the persistence of subclinical psychotic experiences. One of the factors that is likely associated with this persistence is depression. Although commonly viewed as interrelated concepts, the exact relationship between subclinical psychosis and depression is not clear. METHODS Cross-lag...

Poliovirus Particles do not Form in Preinfected Cells with Reovirus

Background and Aims: Inhibition of viral growth in coinfected cells with two different viruses has been described. This phenomenon known as viral interference can occur in several virus host systems such as interference of enterovirus infection on poliovirus vaccine strains. In this study we superinfected reovirus infected HeLa cells with poliovirus to determine if poliovirus can replicate in s...

What do epistemic logic and cognitive science have to do with each other?

Epistemic logic is a multi-faceted theory aimed at targeting notions such as knowledge, belief, information, awareness, memory and other propositional attitudes, by means of logical and semantical tools. These concepts ought to be in the spotlight of cognitive science too, but the two have not yet seriously been explored in cooperation. In this paper, it is shown that a number of possibilities ...

What do Werner and Children’s Reaction to Terrorism have to do with each other